Tag Archives: genetic variation

CSHL’s sequencing power gets a fresh boost

At CSHL’s Woodbury Genome Center a decade ago, it took 12 technicians working in two shifts and six “first generation” sequencing machines to sequence 70 million bases of DNA—repeats of A, T, G, C—in a single month. By 2007, as … Continue reading

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Collaboration column: A new gene-hunting strategy locates genetic cause of a rare disease

With an ingenious combination of next-generation sequencing, conventional gene mapping and bioinformatics detective work, an Israeli-led collaboration that includes CSHL scientists has helped a Palestinian family to confront the genetic culprit behind a rare, hereditary neurological disease that afflicts some … Continue reading

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Collaboration column: SMA therapeutics and potential drug target for schizophrenia

CSHL researchers are part of two highly successful, multi-institutional collaborations that report exciting advances in developing therapeutics for a devastating neuromuscular disorder and in finding a ‘druggable’ target for schizophrenia. For several years now, CSHL’s Adrian Krainer has devoted his expertise in … Continue reading

Posted in Disease research, Genomics, Neuroscience | Tagged , , , , , | 1 Comment